What is the action of clopidogrel?

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It is also used with aspirin to treat new/worsening chest pain (new heart attack, unstable angina) and to keep blood vessels open and prevent blood clots after certain procedures (such as cardiac stent). Clopidogrel works by blocking platelets from sticking together and prevents them from forming harmful clots.

Can clopidogrel be taken every other day? Following 3 months treatment with clopidogrel 75 mg daily (and aspirin 100 mg) patients were randomized to one of two groups: a. Conclusions: This study suggests that effective platelet inhibition can be achieved by tapering of clopidogrel treatment using a strategy of clopidogrel administration every other day.

what is the mechanism of action of clopidogrel?

Mechanism Of Action Clopidogrel is an inhibitor of platelet activation and aggregation through the irreversible binding of its active metabolite to the P2Y12 class of ADP receptors on platelets.

Is there an alternative to clopidogrel? Besides oral anticoagulants, such as warfarin and the more recent dabigatran[9], and niche agents, such as cilostazol and ticlopidine[10,11], the most promising alternatives to clopidogrel in those with background aspirin therapy are prasugrel and ticagrelor.

what type of drug is clopidogrel?

Plavix (clopidogrel bisulfate) is a thienopyridine class of drug that inhibits platelet aggregation and thus inhibits aspects of blood clotting used to treat patients with acute coronary syndrome, myocardial infarction (MI), peripheral vascular disease and some stroke (ischemic type) patients.

Can clopidogrel cause leg pain?

It frequently occurs in the legs and often causes claudication or pain in the legs upon walking.) Clopidogrel bisulfate is used to reduce the risk of heart attacks and strokes in these patients.

what are the side effects of clopidogrel 75 mg?

Common side effects of clopidogrel can include:

Can clopidogrel cause shortness of breath?

Shortness of breath is not a common side effect of Plavix, but it may be symptom of a serious side effect of the drug. Plavix is used to help prevent blood clots from forming in your body. Call your doctor right away if you have any unexplained shortness of breath while you’re taking Plavix.

How long does clopidogrel take to work?

If you take it every day, clopidogrel stops platelets clumping together to form unwanted blood clots. This prevents heart attacks and strokes. How long does it take to work? Clopidogrel works within 2 hours of taking it.

Does clopidogrel make you tired?

Clopidogrel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: excessive tiredness. headache.

Can clopidogrel cause back pain?

Clopidogrel is a commonly prescribed thienopyridine. The most common side effects from clopidogrel use are gastrointestinal problems and an increased risk of bleeding, especially when used in combination with aspirin;9 with back pain and arthralgia each occurring in 6% of patients.

What is the difference between aspirin and clopidogrel?

Plavix (clopidogrel) quick comparison of differences. Aspirin and Plavix (clopidogrel bisulfate) are drugs used to prevent blood clots. Plavix is an anticoagulant and aspirin is a nonsteroidal anti-inflammatory drug (NSAID). Aspirin also is used to reduce fever, and to treat pain and inflammation in the body.

Is clopidogrel better than aspirin?

In summary, clopidogrel appears to be somewhat more effective than aspirin if one is willing to accept the unitary atherosclerosis paradigm. The gain, however, is modest: about 200 patients should use clopidogrel rather than aspirin for 1 year to prevent just one vascular event.

Is clopidogrel a statin?

Statins are lipid-lowering agents, whereas clopidogrel is an antiplatelet agent. Clinicians commonly prescribe both medications for patients to prevent atherosclerotic cardiovascular disease (ASCVD). Clopidogrel is an inactive thienopyridine prodrug that requires activation by CYP2C19, among other isoforms.

How long do you have to take clopidogrel?

The new recommendation is that after 12 months if there is no evidence of major bleeding or other problems with clopidogrel + aspirin, it is suggested you continue that therapy for an additional 18 months.

Can clopidogrel be stopped?

Most experts recommend taking Plavix and aspirin for at least one year after getting a stent, unless the drug causes problems. If necessary, it can be stopped after three months with a bare-metal stent or six months with a drug-releasing stent.